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Cohort

The Cohort computes a cohort of individuals based on specified entry criteria, inclusions, exclusions, and computes baseline characteristics and outcomes from the extracted index dates.

Parameters:

Name Type Description Default
name str

A descriptive name for the cohort.

required
entry_criterion Phenotype

The phenotype used to define index date for the cohort.

required
inclusions Optional[List[Phenotype]]

A list of phenotypes that must evaluate to True for patients to be included in the cohort.

None
exclusions Optional[List[Phenotype]]

A list of phenotypes that must evaluate to False for patients to be included in the cohort.

None
characteristics Optional[List[Phenotype]]

A list of phenotypes representing baseline characteristics of the cohort to be computed for all patients passing the inclusion and exclusion criteria.

None
derived_tables Optional[List[DerivedTable]]

A list of derived tables to compute before the entry stage. Their outputs are available as domains for all subsequent stages.

None
derived_tables_post_entry Optional[List[DerivedTable]]

A list of derived tables to compute after the index stage, using index-subset tables. Their outputs are available as domains for the reporting stage.

None
outcomes Optional[List[Phenotype]]

A list of phenotypes representing outcomes of the cohort.

None
description Optional[str]

A plain text description of the cohort.

None
data_period

Restrict all input data to a specific date range. The input data will be modified to look as if data outside the data_period was never recorded before any phenotypes are computed. See DataPeriodFilterNode for details on how the input data are affected by this parameter.

required
custom_reporters Optional[List]

Additional reporter instances to run on this cohort only, after the default Waterfall and Table1 reporters. Each reporter must implement execute(cohort) and to_json(path).

None

Attributes:

Name Type Description
table PhenotypeTable

The resulting index table after filtering (None until execute is called)

inclusions_table Table

The patient-level result of all inclusion criteria calculations (None until execute is called)

exclusions_table Table

The patient-level result of all exclusion criteria calculations (None until execute is called)

characteristics_table Table

The patient-level result of all baseline characteristics caclulations. (None until execute is called)

outcomes_table Table

The patient-level result of all outcomes caclulations. (None until execute is called)

subset_tables_entry Dict[str, PhenexTable]

Tables that have been subset by those patients satisfying the entry criterion.

subset_tables_index Dict[str, PhenexTable]

Tables that have been subset by those patients satisfying the entry, inclusion and exclusion criteria.

Source code in phenex/core/cohort.py
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class Cohort:
    """
    The Cohort computes a cohort of individuals based on specified entry criteria, inclusions, exclusions, and computes baseline characteristics and outcomes from the extracted index dates.

    Parameters:
        name: A descriptive name for the cohort.
        entry_criterion: The phenotype used to define index date for the cohort.
        inclusions: A list of phenotypes that must evaluate to True for patients to be included in the cohort.
        exclusions: A list of phenotypes that must evaluate to False for patients to be included in the cohort.
        characteristics: A list of phenotypes representing baseline characteristics of the cohort to be computed for all patients passing the inclusion and exclusion criteria.
        derived_tables: A list of derived tables to compute before the entry stage. Their outputs are available as domains for all subsequent stages.
        derived_tables_post_entry: A list of derived tables to compute after the index stage, using index-subset tables. Their outputs are available as domains for the reporting stage.
        outcomes: A list of phenotypes representing outcomes of the cohort.
        description: A plain text description of the cohort.
        data_period: Restrict all input data to a specific date range. The input data will be modified to look as if data outside the data_period was never recorded before any phenotypes are computed. See DataPeriodFilterNode for details on how the input data are affected by this parameter.
        custom_reporters: Additional reporter instances to run on this cohort only, after the default Waterfall and Table1 reporters. Each reporter must implement ``execute(cohort)`` and ``to_json(path)``.

    Attributes:
        table (PhenotypeTable): The resulting index table after filtering (None until execute is called)
        inclusions_table (Table): The patient-level result of all inclusion criteria calculations (None until execute is called)
        exclusions_table (Table): The patient-level result of all exclusion criteria calculations (None until execute is called)
        characteristics_table (Table): The patient-level result of all baseline characteristics caclulations. (None until execute is called)
        outcomes_table (Table): The patient-level result of all outcomes caclulations. (None until execute is called)
        subset_tables_entry (Dict[str, PhenexTable]): Tables that have been subset by those patients satisfying the entry criterion.
        subset_tables_index (Dict[str, PhenexTable]): Tables that have been subset by those patients satisfying the entry, inclusion and exclusion criteria.
    """

    def __init__(
        self,
        name: str,
        entry_criterion: Phenotype,
        inclusions: Optional[List[Phenotype]] = None,
        exclusions: Optional[List[Phenotype]] = None,
        characteristics: Optional[List[Phenotype]] = None,
        derived_tables: Optional[List["DerivedTable"]] = None,
        derived_tables_post_entry: Optional[List["DerivedTable"]] = None,
        outcomes: Optional[List[Phenotype]] = None,
        description: Optional[str] = None,
        database: Optional[Database] = None,
        custom_reporters: Optional[List] = None,
    ):
        self.name = name
        self.description = description
        self.database = database
        self.table = None  # Will be set during execution to index table
        self.subset_tables_entry = None  # Will be set during execution
        self.subset_tables_index = None  # Will be set during execution
        self.entry_criterion = entry_criterion
        self.inclusions = self._flatten(inclusions)
        self.exclusions = self._flatten(exclusions)

        # characteristics may be a flat list or a dict of {section_name: [phenotypes]}
        if isinstance(characteristics, dict):
            self.characteristic_sections = {
                section: [p.display_name for p in phenos]
                for section, phenos in characteristics.items()
            }
            self.characteristics = [
                p for phenos in characteristics.values() for p in phenos
            ]
        else:
            self.characteristic_sections = None
            self.characteristics = self._flatten(characteristics)

        self.derived_tables = derived_tables
        self.derived_tables_post_entry = derived_tables_post_entry
        self.outcomes = self._flatten(outcomes)
        self.custom_reporters = custom_reporters or []
        self.n_persons_in_source_database = None

        self.phenotypes = (
            [self.entry_criterion]
            + self.inclusions
            + self.exclusions
            + self.characteristics
            + self.outcomes
        )

        self._validate_node_uniqueness()

        # stages: set at execute() time
        self.data_period_filter_stage = None
        self.derived_tables_stage = None
        self.entry_stage = None
        self.index_stage = None
        self.derived_tables_post_entry_stage = None
        self.reporting_stage = None

        # special Nodes that Cohort builds (later, in build_stages())
        # need to be able to refer to later to get outputs
        self.inclusions_table_node = None
        self.exclusions_table_node = None
        self.characteristics_table_node = None
        self.outcomes_table_node = None
        self.index_table_node = None
        self.subset_tables_entry_nodes = None
        self.subset_tables_index_nodes = None
        self.table1_node = None
        self.table1_detailed_node = None
        self.table1_outcomes_node = None
        self.table1_outcomes_detailed_node = None
        self.waterfall_node = None
        self.waterfall_detailed_node = None
        self.custom_reporter_nodes = []

        logger.info(
            f"Cohort '{self.name}' initialized with entry criterion '{self.entry_criterion.name}'"
        )

    @staticmethod
    def _flatten(items: Optional[List]) -> List:
        """Flatten one level of nesting, so both [p1, p2] and [[p1, p2]] work."""
        if not items:
            return []
        result = []
        for item in items:
            if isinstance(item, list):
                result.extend(item)
            else:
                result.append(item)
        return result

    def _validate_node_uniqueness(self):
        # Use Node's capability to check for node uniqueness rather than reimplementing it here
        Node().add_children(self.phenotypes)

    def build_stages(self, tables: Dict[str, PhenexTable]):
        """
        Build the computational stages for cohort execution.

        This method constructs the directed acyclic graph (DAG) of computational stages required to execute the cohort. The stages are built in dependency order and include:

        1. **Derived Tables Stage** (optional): Executes any derived table computations
        2. **Entry Stage**: Computes entry phenotype and subsets tables filtered by the entry criterion phenotype
        3. **Index Stage**: Applies inclusion/exclusion criteria and creates the final index table
        4. **Reporting Stage** (optional): Computes characteristics and outcomes tables

        Parameters:
            tables: Dictionary mapping domain names to PhenexTable objects containing the source data tables required for phenotype computation.

        Raises:
            ValueError: If required domains are missing from the input tables.

        Side Effects:
            Sets the following instance attributes:
            - self.entry_stage: NodeGroup for entry criterion processing
            - self.derived_tables_stage: NodeGroup for derived tables (if any)
            - self.index_stage: NodeGroup for inclusion/exclusion processing
            - self.reporting_stage: NodeGroup for characteristics/outcomes (if any)
            - Various table nodes for accessing intermediate results

        Note:
            This method must be called before execute() to initialize the computation graph.
            Node uniqueness is validated across all stages to prevent naming conflicts.
        """
        # Check required domains are present to fail early (note this check is not perfect as _get_domains() doesn't catch everything, e.g., intermediate tables in autojoins, but this is better than nothing)
        # Filter out None tables (tables not found in source data)
        available_tables = {k: v for k, v in tables.items() if v is not None}

        # If a derived table has the same name as a mapped table, the mapped table must be
        # discarded — otherwise _get_subset_tables_nodes would produce two SubsetTable nodes
        # with identical names, causing a duplicate-node error in the execution graph.
        all_derived = list(self.derived_tables or []) + list(
            self.derived_tables_post_entry or []
        )
        for dt in all_derived:
            if dt.name in available_tables:
                logger.warning(
                    f"Derived table '{dt.name}' has the same name as a provided mapped table. "
                    f"The mapped table will be discarded and the derived table will be used for domain '{dt.name}'."
                )
                del available_tables[dt.name]

        domains = list(available_tables.keys())
        required_domains = self._get_domains()

        missing_domains = [d for d in required_domains if d not in domains]
        if missing_domains:
            logger.warning(
                f"Some required domains are not present in input tables: {missing_domains}. "
                f"Phenotypes requiring these domains may fail during execution."
            )

        #
        # Data period filter stage: OPTIONAL
        #
        self.data_period_filter_stage = None
        self.derived_tables_stage = None
        self.derived_tables_post_entry_stage = None
        if self.database and self.database.data_period:
            data_period_filter_nodes = [
                DataPeriodFilterNode(
                    name=f"{self.name}__data_period_filter_{domain}".upper(),
                    domain=domain,
                    date_filter=self.database.data_period,
                )
                for domain in domains
            ]
            self.data_period_filter_stage = NodeGroup(
                name="data_period_filter", nodes=data_period_filter_nodes
            )

        #
        # Derived tables pre-entry stage: OPTIONAL
        #
        if self.derived_tables:
            self.derived_tables_stage = NodeGroup(
                name="derived_tables_stage", nodes=self.derived_tables
            )

        #
        # Entry stage: REQUIRED
        #
        # Pre-entry derived table outputs become new domains available from the entry stage onward.
        pre_entry_derived_domains = [x.name for x in (self.derived_tables or [])]
        entry_domains = domains + pre_entry_derived_domains
        self.subset_tables_entry_nodes = self._get_subset_tables_nodes(
            stage="subset_entry",
            domains=entry_domains,
            index_phenotype=self.entry_criterion,
        )
        self.entry_stage = NodeGroup(
            name="entry_stage", nodes=self.subset_tables_entry_nodes
        )
        #

        # Derived tables post-entry stage: OPTIONAL
        #
        if self.derived_tables_post_entry:
            self.derived_tables_post_entry_stage = NodeGroup(
                name="derived_tables_post_entry_stage",
                nodes=self.derived_tables_post_entry,
            )

        #
        # Index stage: REQUIRED
        #
        index_nodes = []
        if self.inclusions:
            self.inclusions_table_node = InclusionsTableNode(
                name=f"{self.name}__inclusions".upper(),
                index_phenotype=self.entry_criterion,
                phenotypes=self.inclusions,
            )
            index_nodes.append(self.inclusions_table_node)
        if self.exclusions:
            self.exclusions_table_node = ExclusionsTableNode(
                name=f"{self.name}__exclusions".upper(),
                index_phenotype=self.entry_criterion,
                phenotypes=self.exclusions,
            )
            index_nodes.append(self.exclusions_table_node)

        self.index_table_node = IndexPhenotype(
            f"{self.name}__index".upper(),
            entry_phenotype=self.entry_criterion,
            inclusion_table_node=self.inclusions_table_node,
            exclusion_table_node=self.exclusions_table_node,
        )
        index_nodes.append(self.index_table_node)

        # Add Waterfall node after index table (depends on index_table_node)
        self.waterfall_node = WaterfallNode(
            name=f"{self.name}__waterfall".upper(),
            cohort=self,
            index_table_node=self.index_table_node,
        )
        index_nodes.append(self.waterfall_node)
        self.waterfall_detailed_node = WaterfallNode(
            name=f"{self.name}__waterfall_detailed".upper(),
            cohort=self,
            index_table_node=self.index_table_node,
            include_component_phenotypes_level=100,  # include all component phenotypes in the detailed waterfall report
        )
        index_nodes.append(self.waterfall_detailed_node)

        self.subset_tables_index_nodes = self._get_subset_tables_nodes(
            stage="subset_index",
            domains=entry_domains,
            index_phenotype=self.index_table_node,
        )
        self.index_stage = NodeGroup(
            name="index_stage",
            nodes=self.subset_tables_index_nodes + index_nodes,
        )

        #
        # Post-index / reporting stage: OPTIONAL
        #
        reporting_nodes = []

        if self.characteristics:
            self.characteristics_table_node = HStackNode(
                name=f"{self.name}__characteristics".upper(),
                phenotypes=self.characteristics,
                join_table=self.index_table_node,
            )
            reporting_nodes.append(self.characteristics_table_node)
        if self.outcomes:
            self.outcomes_table_node = HStackNode(
                name=f"{self.name}__outcomes".upper(),
                phenotypes=self.outcomes,
                join_table=self.index_table_node,
            )
            reporting_nodes.append(self.outcomes_table_node)

        # Add Table1 node if there are characteristics
        if self.characteristics:
            self.table1_node = Table1Node(
                name=f"{self.name}__table1".upper(),
                cohort=self,
            )
            reporting_nodes.append(self.table1_node)
            self.table1_detailed_node = Table1Node(
                name=f"{self.name}__table1_detailed".upper(),
                cohort=self,
                include_component_phenotypes_level=100,
            )
            reporting_nodes.append(self.table1_detailed_node)

        # Add Table1OutcomesNode if there are outcomes
        if self.outcomes:
            self.table1_outcomes_node = Table1OutcomesNode(
                name=f"{self.name}__table1_outcomes".upper(),
                cohort=self,
            )
            reporting_nodes.append(self.table1_outcomes_node)
            self.table1_outcomes_detailed_node = Table1OutcomesNode(
                name=f"{self.name}__table1_outcomes_detailed".upper(),
                cohort=self,
                include_component_phenotypes_level=100,
            )
            reporting_nodes.append(self.table1_outcomes_detailed_node)

        # Add CustomReporterNodes for each custom reporter
        self.custom_reporter_nodes = []
        for reporter in self.custom_reporters:
            node = CustomReporterNode(
                name=f"{self.name}__custom__{reporter.name}".upper(),
                cohort=self,
                reporter=reporter,
            )
            self.custom_reporter_nodes.append(node)
            reporting_nodes.append(node)

        if reporting_nodes:
            self.reporting_stage = NodeGroup(
                name="reporting_stage", nodes=reporting_nodes
            )

    def _get_domains(self):
        """
        Get a list of all domains used by any phenotype in this cohort.
        """
        top_level_nodes = (
            [self.entry_criterion]
            + self.inclusions
            + self.exclusions
            + self.characteristics
            + self.outcomes
        )
        all_nodes = top_level_nodes + sum([t.dependencies for t in top_level_nodes], [])

        # FIXME Person domain should not be HARD CODED; however, it IS hardcoded in SCORE phenotype. Remove hardcoding!
        domains = ["PERSON"] + [
            getattr(pt, "domain", None)
            for pt in all_nodes
            if getattr(pt, "domain", None) is not None
        ]

        domains += [
            getattr(getattr(pt, "categorical_filter", None), "domain", None)
            for pt in all_nodes
            if getattr(getattr(pt, "categorical_filter", None), "domain", None)
            is not None
        ]
        domains = list(set(domains))
        return domains

    def _get_subset_tables_nodes(
        self, stage: str, domains: List[str], index_phenotype: Phenotype
    ):
        """
        Get the nodes for subsetting tables for all domains in this cohort subsetting by the given index_phenotype.

        stage: A string for naming the nodes.
        domains: List of domains to subset.
        index_phenotype: The phenotype to use for subsetting patients.
        """
        return [
            SubsetTable(
                name=f"{self.name}__{stage}_{domain}".upper(),
                domain=domain,
                index_phenotype=index_phenotype,
            )
            for domain in domains
        ]

    @property
    def inclusions_table(self):
        if self.inclusions_table_node:
            return self.inclusions_table_node.table

    @property
    def exclusions_table(self):
        if self.exclusions_table_node:
            return self.exclusions_table_node.table

    @property
    def index_table(self):
        return self.index_table_node.table

    @property
    def characteristics_table(self):
        if self.characteristics_table_node:
            return self.characteristics_table_node.table

    @property
    def outcomes_table(self):
        if self.outcomes_table_node:
            return self.outcomes_table_node.table

    def get_subset_tables_entry(self, tables):
        """
        Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given entry_phenotype.
        """
        subset_tables_entry = {}
        for node in self.subset_tables_entry_nodes:
            # Skip if table is None (not found in source data)
            if node.table is None:
                continue
            if tables[node.domain] is None:
                continue
            subset_tables_entry[node.domain] = type(tables[node.domain])(node.table)
        return subset_tables_entry

    def get_subset_tables_index(self, tables):
        """
        Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given index_phenotype.
        """
        subset_tables_index = {}
        for node in self.subset_tables_index_nodes:
            # Skip if table is None (not found in source data)
            if node.table is None:
                continue
            if tables.get(node.domain) is None:
                continue
            subset_tables_index[node.domain] = type(tables[node.domain])(node.table)
        return subset_tables_index

    def execute(
        self,
        tables: Dict[str, PhenexTable] = None,
        con: Optional["SnowflakeConnector"] = None,
        overwrite: Optional[bool] = False,
        n_threads: Optional[int] = 1,
        lazy_execution: Optional[bool] = False,
    ):
        """
        The execute method executes the full cohort in order of computation. The order is data period filter -> derived tables -> entry criterion -> inclusion -> exclusion -> baseline characteristics. Tables are subset at two points, after entry criterion and after full inclusion/exclusion calculation to result in subset_entry data (contains all source data for patients that fulfill the entry criterion, with a possible index date) and subset_index data (contains all source data for patients that fulfill all in/ex criteria, with a set index date). Additionally, default reporters are executed such as table 1 for baseline characteristics.

        There are two ways to use the execute method and thus execute a cohort:

        1. Directly passing source data in the `tables` dictionary
        ```python
        tables = con.get_mapped_tables(mapper)
        cohort.execute(tables)
        ```
        2. Indirectly by defining the data source using the con and mapped_tables keyword arguments at initialization. The source data `tables` is then retrieved at execution time
        ```python
        cohort = Cohort(
            con=SnowflakeConnector(),
            mapper= OMOPDomains,
            ...
        )
        cohort.execute()
        ````

        Parameters:
            tables: A dictionary mapping domains to Table objects. This is optional if the Cohort was initialized with a con and mapper. If passed, this takes precedence over the con and mapper defined at initialization.
            con: Database connector for materializing outputs. If passed, this takes precedence over the con defined at initialization.
            overwrite: Whether to overwrite existing tables
            lazy_execution: Whether to use lazy execution with change detection
            n_threads: Max number of jobs to run simultaneously.

        Returns:
            PhenotypeTable: The index table corresponding the cohort.
        """

        con = self._prepare_database_connector_for_execution(con)
        tables = self._prepare_tables_for_execution(con, tables)

        self.n_persons_in_source_database = (
            tables["PERSON"].distinct().count().execute()
        )

        self.build_stages(tables)

        # Apply data period filter first if specified
        if self.data_period_filter_stage:
            logger.info(f"Cohort '{self.name}': executing data period filter stage ...")
            self.data_period_filter_stage.execute(
                tables=tables,
                con=con,
                overwrite=overwrite,
                n_threads=n_threads,
                lazy_execution=lazy_execution,
            )
            # Update tables with filtered versions (only when the node actually modified the table;
            # nodes with no relevant date columns return None and the original table is kept)
            for node in self.data_period_filter_stage.children:
                if node.table is not None:
                    tables[node.domain] = node.table
            logger.info(f"Cohort '{self.name}': completed data period filter stage.")

        if self.derived_tables_stage:
            logger.info(
                f"Cohort '{self.name}': executing derived tables pre-entry stage ..."
            )
            self.derived_tables_stage.execute(
                tables=tables,
                con=con,
                overwrite=overwrite,
                n_threads=n_threads,
                lazy_execution=lazy_execution,
            )
            logger.info(
                f"Cohort '{self.name}': completed derived tables pre-entry stage."
            )
            for node in self.derived_tables:
                tables[node.name] = PhenexTable(node.table)

        logger.info(f"Cohort '{self.name}': executing entry stage ...")

        self.entry_stage.execute(
            tables=tables,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )
        self.subset_tables_entry = tables = self.get_subset_tables_entry(tables)

        logger.info(f"Cohort '{self.name}': completed entry stage.")

        if self.derived_tables_post_entry_stage:
            logger.info(
                f"Cohort '{self.name}': executing derived tables post-entry stage ..."
            )
            self.derived_tables_post_entry_stage.execute(
                tables=self.subset_tables_entry,
                con=con,
                overwrite=overwrite,
                n_threads=n_threads,
                lazy_execution=lazy_execution,
            )
            logger.info(
                f"Cohort '{self.name}': completed derived tables post-entry stage."
            )
            entry_dates = self.entry_criterion.table.select(
                "PERSON_ID", "EVENT_DATE"
            ).rename({"INDEX_DATE": "EVENT_DATE"})
            # TODO this is a bit hacky, consider a cleaner way to handle this if we want to support post-entry derived tables in the long term i.e. a DERIVED_TABLES class that adds index table automatically if present in the source derived table.
            for node in self.derived_tables_post_entry:
                table_with_index = node.table.join(entry_dates, "PERSON_ID")
                self.subset_tables_entry[node.name] = PhenexTable(table_with_index)
            tables = self.subset_tables_entry

        logger.info(f"Cohort '{self.name}': executing index stage ...")

        self.index_stage.execute(
            tables=self.subset_tables_entry,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )
        self.table = self.index_table_node.table

        logger.info(f"Cohort '{self.name}': completed index stage.")
        logger.info(f"Cohort '{self.name}': executing reporting stage ...")

        self.subset_tables_index = self.get_subset_tables_index(tables)

        # Also add derived post-entry tables to subset_tables_index, further filtered
        # to only include persons that passed all inclusion/exclusion criteria.
        if self.derived_tables_post_entry:
            index_person_ids = self.index_table_node.table.select("PERSON_ID")
            for node in self.derived_tables_post_entry:
                if node.name in self.subset_tables_entry:
                    entry_tbl = self.subset_tables_entry[node.name]
                    filtered_ibis = entry_tbl.table.semi_join(
                        index_person_ids, "PERSON_ID"
                    )
                    self.subset_tables_index[node.name] = type(entry_tbl)(filtered_ibis)

        if self.reporting_stage:
            logger.info(f"Cohort '{self.name}': executing reporting stage ...")
            self.reporting_stage.execute(
                tables=self.subset_tables_index,
                con=con,
                overwrite=overwrite,
                n_threads=n_threads,
                lazy_execution=lazy_execution,
            )

        return self.index_table

    def _prepare_database_connector_for_execution(self, con):
        """
        identify correct connector for cohort execution. If a connector is passed to execute(), use that. Else, if a connector was defined at initialization, use that. Else, raise an error since no connector was provided.
        Parameters:
            con: A database connector passed to execute(). This takes precedence over any connector defined at initialization.
        """
        if con is not None:
            if self.database is not None and con != self.database.connector:
                logger.warning(
                    "Cohort was initialized with a different connector than the one passed to execute(). Using the passed connector."
                )
            return con
        elif self.database is not None:
            logger.warning(
                "Cohort was initialized with a connector but none was passed to execute(). Using the connector from initialization."
            )
            return self.database.connector
        else:
            logger.warning("No database connector provided for cohort execution!")

    def _prepare_tables_for_execution(self, con, tables):
        """
        Docstring for _prepare_tables_for_execution

        Parameters:
            con: A database connector to use for retrieving tables if tables are not passed directly. This is required if tables are not passed directly and the Cohort was initialized with a database.
            tables: Tables passed to execute(). This takes precedence over any tables retrieved from the database defined at initialization.
        """
        if tables is not None:
            return tables
        elif self.database is not None:
            if self.database.mapper is not None:
                logger.warning(
                    "Cohort was initialized with a mapper but no tables were passed to execute(). Using the mapper to retrieve tables for execution."
                )
                tables = self.database.mapper.get_mapped_tables(con)
                return tables
            else:
                raise ValueError(
                    "Cohort was initialized with a database but no tables were passed to execute() and no mapper was defined in the database to retrieve tables for execution!"
                )
        else:
            raise ValueError(
                "No tables provided for cohort execution and no database defined to retrieve tables for execution!"
            )

    @property
    def table1(self):
        """Get the Table1 report DataFrame from the table1_node if it exists."""
        if self.table1_node:
            return self.table1_node.df_report
        return None

    @property
    def waterfall(self):
        """Get the Waterfall report DataFrame from the waterfall_node if it exists."""
        if self.waterfall_node:
            return self.waterfall_node.df_report
        return None

    @property
    def waterfall_detailed(self):
        """Get the detailed Waterfall report DataFrame from the waterfall_node if it exists."""
        if self.waterfall_detailed_node:
            return self.waterfall_detailed_node.df_report
        return None

    def write_reports_to_excel(self, path: str):
        """Write all available reports (table1, waterfall, waterfall_detailed) to Excel files in the given directory."""
        if self.table1_node:
            self.table1_node.to_excel(os.path.join(path, "table1.xlsx"))
        if self.table1_detailed_node:
            self.table1_detailed_node.to_excel(
                os.path.join(path, "table1_detailed.xlsx")
            )
        if self.table1_outcomes_node:
            self.table1_outcomes_node.to_excel(
                os.path.join(path, "table1_outcomes.xlsx")
            )
        if self.table1_outcomes_detailed_node:
            self.table1_outcomes_detailed_node.to_excel(
                os.path.join(path, "table1_outcomes_detailed.xlsx")
            )
        if self.waterfall_node:
            self.waterfall_node.to_excel(os.path.join(path, "waterfall.xlsx"))
        if self.waterfall_detailed_node:
            self.waterfall_detailed_node.to_excel(
                os.path.join(path, "waterfall_detailed.xlsx")
            )
        for custom_reporter_node in self.custom_reporter_nodes:
            report_filename = custom_reporter_node.reporter.name
            custom_reporter_node.to_excel(os.path.join(path, report_filename + ".xlsx"))

    def write_reports_to_json(self, path: str):
        """Write all available reports as JSON files (machine-readable intermediate format)."""
        if self.table1_node:
            self.table1_node.to_json(os.path.join(path, "table1.json"))
        if self.table1_detailed_node:
            self.table1_detailed_node.to_json(
                os.path.join(path, "table1_detailed.json")
            )
        if self.table1_outcomes_node:
            self.table1_outcomes_node.to_json(
                os.path.join(path, "table1_outcomes.json")
            )
        if self.table1_outcomes_detailed_node:
            self.table1_outcomes_detailed_node.to_json(
                os.path.join(path, "table1_outcomes_detailed.json")
            )
        if self.waterfall_node:
            self.waterfall_node.to_json(os.path.join(path, "waterfall.json"))
        if self.waterfall_detailed_node:
            self.waterfall_detailed_node.to_json(
                os.path.join(path, "waterfall_detailed.json")
            )
        for custom_reporter_node in self.custom_reporter_nodes:
            report_filename = custom_reporter_node.reporter.name
            custom_reporter_node.to_json(os.path.join(path, report_filename + ".json"))

    def to_dict(self):
        """
        Return a dictionary representation of the Node. The dictionary must contain all dependencies of the Node such that if anything in self.to_dict() changes, the Node must be recomputed.
        """
        d = to_dict(self)
        # custom_reporters are runtime execution objects and cannot be meaningfully
        # serialized; drop them from the frozen cohort definition.
        d.pop("custom_reporters", None)
        return d

    def get_codelists(self, as_dataframe=False):
        """
        Get a dictionary of all codelists used in any phenotype in this cohort. The keys are the codelist names and the values are the codelist objects.
        """
        top_level_nodes = (
            [self.entry_criterion]
            + self.inclusions
            + self.exclusions
            + self.characteristics
            + self.outcomes
        )
        all_nodes = top_level_nodes + sum([t.dependencies for t in top_level_nodes], [])
        codelists = {
            pt.display_name: pt.codelist
            for pt in all_nodes
            if getattr(pt, "codelist", None) is not None
        }
        if as_dataframe:
            import pandas as pd

            _dfs = []
            for name_pt, codelist in codelists.items():
                codelist_df = codelist.df
                codelist_df["phenotype"] = name_pt
                _dfs.append(codelist_df)
            codelists_df = pd.concat(_dfs, ignore_index=True)
            return codelists_df

        return codelists

table1 property

Get the Table1 report DataFrame from the table1_node if it exists.

waterfall property

Get the Waterfall report DataFrame from the waterfall_node if it exists.

waterfall_detailed property

Get the detailed Waterfall report DataFrame from the waterfall_node if it exists.

build_stages(tables)

Build the computational stages for cohort execution.

This method constructs the directed acyclic graph (DAG) of computational stages required to execute the cohort. The stages are built in dependency order and include:

  1. Derived Tables Stage (optional): Executes any derived table computations
  2. Entry Stage: Computes entry phenotype and subsets tables filtered by the entry criterion phenotype
  3. Index Stage: Applies inclusion/exclusion criteria and creates the final index table
  4. Reporting Stage (optional): Computes characteristics and outcomes tables

Parameters:

Name Type Description Default
tables Dict[str, PhenexTable]

Dictionary mapping domain names to PhenexTable objects containing the source data tables required for phenotype computation.

required

Raises:

Type Description
ValueError

If required domains are missing from the input tables.

Side Effects

Sets the following instance attributes: - self.entry_stage: NodeGroup for entry criterion processing - self.derived_tables_stage: NodeGroup for derived tables (if any) - self.index_stage: NodeGroup for inclusion/exclusion processing - self.reporting_stage: NodeGroup for characteristics/outcomes (if any) - Various table nodes for accessing intermediate results

Note

This method must be called before execute() to initialize the computation graph. Node uniqueness is validated across all stages to prevent naming conflicts.

Source code in phenex/core/cohort.py
def build_stages(self, tables: Dict[str, PhenexTable]):
    """
    Build the computational stages for cohort execution.

    This method constructs the directed acyclic graph (DAG) of computational stages required to execute the cohort. The stages are built in dependency order and include:

    1. **Derived Tables Stage** (optional): Executes any derived table computations
    2. **Entry Stage**: Computes entry phenotype and subsets tables filtered by the entry criterion phenotype
    3. **Index Stage**: Applies inclusion/exclusion criteria and creates the final index table
    4. **Reporting Stage** (optional): Computes characteristics and outcomes tables

    Parameters:
        tables: Dictionary mapping domain names to PhenexTable objects containing the source data tables required for phenotype computation.

    Raises:
        ValueError: If required domains are missing from the input tables.

    Side Effects:
        Sets the following instance attributes:
        - self.entry_stage: NodeGroup for entry criterion processing
        - self.derived_tables_stage: NodeGroup for derived tables (if any)
        - self.index_stage: NodeGroup for inclusion/exclusion processing
        - self.reporting_stage: NodeGroup for characteristics/outcomes (if any)
        - Various table nodes for accessing intermediate results

    Note:
        This method must be called before execute() to initialize the computation graph.
        Node uniqueness is validated across all stages to prevent naming conflicts.
    """
    # Check required domains are present to fail early (note this check is not perfect as _get_domains() doesn't catch everything, e.g., intermediate tables in autojoins, but this is better than nothing)
    # Filter out None tables (tables not found in source data)
    available_tables = {k: v for k, v in tables.items() if v is not None}

    # If a derived table has the same name as a mapped table, the mapped table must be
    # discarded — otherwise _get_subset_tables_nodes would produce two SubsetTable nodes
    # with identical names, causing a duplicate-node error in the execution graph.
    all_derived = list(self.derived_tables or []) + list(
        self.derived_tables_post_entry or []
    )
    for dt in all_derived:
        if dt.name in available_tables:
            logger.warning(
                f"Derived table '{dt.name}' has the same name as a provided mapped table. "
                f"The mapped table will be discarded and the derived table will be used for domain '{dt.name}'."
            )
            del available_tables[dt.name]

    domains = list(available_tables.keys())
    required_domains = self._get_domains()

    missing_domains = [d for d in required_domains if d not in domains]
    if missing_domains:
        logger.warning(
            f"Some required domains are not present in input tables: {missing_domains}. "
            f"Phenotypes requiring these domains may fail during execution."
        )

    #
    # Data period filter stage: OPTIONAL
    #
    self.data_period_filter_stage = None
    self.derived_tables_stage = None
    self.derived_tables_post_entry_stage = None
    if self.database and self.database.data_period:
        data_period_filter_nodes = [
            DataPeriodFilterNode(
                name=f"{self.name}__data_period_filter_{domain}".upper(),
                domain=domain,
                date_filter=self.database.data_period,
            )
            for domain in domains
        ]
        self.data_period_filter_stage = NodeGroup(
            name="data_period_filter", nodes=data_period_filter_nodes
        )

    #
    # Derived tables pre-entry stage: OPTIONAL
    #
    if self.derived_tables:
        self.derived_tables_stage = NodeGroup(
            name="derived_tables_stage", nodes=self.derived_tables
        )

    #
    # Entry stage: REQUIRED
    #
    # Pre-entry derived table outputs become new domains available from the entry stage onward.
    pre_entry_derived_domains = [x.name for x in (self.derived_tables or [])]
    entry_domains = domains + pre_entry_derived_domains
    self.subset_tables_entry_nodes = self._get_subset_tables_nodes(
        stage="subset_entry",
        domains=entry_domains,
        index_phenotype=self.entry_criterion,
    )
    self.entry_stage = NodeGroup(
        name="entry_stage", nodes=self.subset_tables_entry_nodes
    )
    #

    # Derived tables post-entry stage: OPTIONAL
    #
    if self.derived_tables_post_entry:
        self.derived_tables_post_entry_stage = NodeGroup(
            name="derived_tables_post_entry_stage",
            nodes=self.derived_tables_post_entry,
        )

    #
    # Index stage: REQUIRED
    #
    index_nodes = []
    if self.inclusions:
        self.inclusions_table_node = InclusionsTableNode(
            name=f"{self.name}__inclusions".upper(),
            index_phenotype=self.entry_criterion,
            phenotypes=self.inclusions,
        )
        index_nodes.append(self.inclusions_table_node)
    if self.exclusions:
        self.exclusions_table_node = ExclusionsTableNode(
            name=f"{self.name}__exclusions".upper(),
            index_phenotype=self.entry_criterion,
            phenotypes=self.exclusions,
        )
        index_nodes.append(self.exclusions_table_node)

    self.index_table_node = IndexPhenotype(
        f"{self.name}__index".upper(),
        entry_phenotype=self.entry_criterion,
        inclusion_table_node=self.inclusions_table_node,
        exclusion_table_node=self.exclusions_table_node,
    )
    index_nodes.append(self.index_table_node)

    # Add Waterfall node after index table (depends on index_table_node)
    self.waterfall_node = WaterfallNode(
        name=f"{self.name}__waterfall".upper(),
        cohort=self,
        index_table_node=self.index_table_node,
    )
    index_nodes.append(self.waterfall_node)
    self.waterfall_detailed_node = WaterfallNode(
        name=f"{self.name}__waterfall_detailed".upper(),
        cohort=self,
        index_table_node=self.index_table_node,
        include_component_phenotypes_level=100,  # include all component phenotypes in the detailed waterfall report
    )
    index_nodes.append(self.waterfall_detailed_node)

    self.subset_tables_index_nodes = self._get_subset_tables_nodes(
        stage="subset_index",
        domains=entry_domains,
        index_phenotype=self.index_table_node,
    )
    self.index_stage = NodeGroup(
        name="index_stage",
        nodes=self.subset_tables_index_nodes + index_nodes,
    )

    #
    # Post-index / reporting stage: OPTIONAL
    #
    reporting_nodes = []

    if self.characteristics:
        self.characteristics_table_node = HStackNode(
            name=f"{self.name}__characteristics".upper(),
            phenotypes=self.characteristics,
            join_table=self.index_table_node,
        )
        reporting_nodes.append(self.characteristics_table_node)
    if self.outcomes:
        self.outcomes_table_node = HStackNode(
            name=f"{self.name}__outcomes".upper(),
            phenotypes=self.outcomes,
            join_table=self.index_table_node,
        )
        reporting_nodes.append(self.outcomes_table_node)

    # Add Table1 node if there are characteristics
    if self.characteristics:
        self.table1_node = Table1Node(
            name=f"{self.name}__table1".upper(),
            cohort=self,
        )
        reporting_nodes.append(self.table1_node)
        self.table1_detailed_node = Table1Node(
            name=f"{self.name}__table1_detailed".upper(),
            cohort=self,
            include_component_phenotypes_level=100,
        )
        reporting_nodes.append(self.table1_detailed_node)

    # Add Table1OutcomesNode if there are outcomes
    if self.outcomes:
        self.table1_outcomes_node = Table1OutcomesNode(
            name=f"{self.name}__table1_outcomes".upper(),
            cohort=self,
        )
        reporting_nodes.append(self.table1_outcomes_node)
        self.table1_outcomes_detailed_node = Table1OutcomesNode(
            name=f"{self.name}__table1_outcomes_detailed".upper(),
            cohort=self,
            include_component_phenotypes_level=100,
        )
        reporting_nodes.append(self.table1_outcomes_detailed_node)

    # Add CustomReporterNodes for each custom reporter
    self.custom_reporter_nodes = []
    for reporter in self.custom_reporters:
        node = CustomReporterNode(
            name=f"{self.name}__custom__{reporter.name}".upper(),
            cohort=self,
            reporter=reporter,
        )
        self.custom_reporter_nodes.append(node)
        reporting_nodes.append(node)

    if reporting_nodes:
        self.reporting_stage = NodeGroup(
            name="reporting_stage", nodes=reporting_nodes
        )

execute(tables=None, con=None, overwrite=False, n_threads=1, lazy_execution=False)

The execute method executes the full cohort in order of computation. The order is data period filter -> derived tables -> entry criterion -> inclusion -> exclusion -> baseline characteristics. Tables are subset at two points, after entry criterion and after full inclusion/exclusion calculation to result in subset_entry data (contains all source data for patients that fulfill the entry criterion, with a possible index date) and subset_index data (contains all source data for patients that fulfill all in/ex criteria, with a set index date). Additionally, default reporters are executed such as table 1 for baseline characteristics.

There are two ways to use the execute method and thus execute a cohort:

  1. Directly passing source data in the tables dictionary
    tables = con.get_mapped_tables(mapper)
    cohort.execute(tables)
    
  2. Indirectly by defining the data source using the con and mapped_tables keyword arguments at initialization. The source data tables is then retrieved at execution time ```python cohort = Cohort( con=SnowflakeConnector(), mapper= OMOPDomains, ... ) cohort.execute() ````

Parameters:

Name Type Description Default
tables Dict[str, PhenexTable]

A dictionary mapping domains to Table objects. This is optional if the Cohort was initialized with a con and mapper. If passed, this takes precedence over the con and mapper defined at initialization.

None
con Optional[SnowflakeConnector]

Database connector for materializing outputs. If passed, this takes precedence over the con defined at initialization.

None
overwrite Optional[bool]

Whether to overwrite existing tables

False
lazy_execution Optional[bool]

Whether to use lazy execution with change detection

False
n_threads Optional[int]

Max number of jobs to run simultaneously.

1

Returns:

Name Type Description
PhenotypeTable

The index table corresponding the cohort.

Source code in phenex/core/cohort.py
def execute(
    self,
    tables: Dict[str, PhenexTable] = None,
    con: Optional["SnowflakeConnector"] = None,
    overwrite: Optional[bool] = False,
    n_threads: Optional[int] = 1,
    lazy_execution: Optional[bool] = False,
):
    """
    The execute method executes the full cohort in order of computation. The order is data period filter -> derived tables -> entry criterion -> inclusion -> exclusion -> baseline characteristics. Tables are subset at two points, after entry criterion and after full inclusion/exclusion calculation to result in subset_entry data (contains all source data for patients that fulfill the entry criterion, with a possible index date) and subset_index data (contains all source data for patients that fulfill all in/ex criteria, with a set index date). Additionally, default reporters are executed such as table 1 for baseline characteristics.

    There are two ways to use the execute method and thus execute a cohort:

    1. Directly passing source data in the `tables` dictionary
    ```python
    tables = con.get_mapped_tables(mapper)
    cohort.execute(tables)
    ```
    2. Indirectly by defining the data source using the con and mapped_tables keyword arguments at initialization. The source data `tables` is then retrieved at execution time
    ```python
    cohort = Cohort(
        con=SnowflakeConnector(),
        mapper= OMOPDomains,
        ...
    )
    cohort.execute()
    ````

    Parameters:
        tables: A dictionary mapping domains to Table objects. This is optional if the Cohort was initialized with a con and mapper. If passed, this takes precedence over the con and mapper defined at initialization.
        con: Database connector for materializing outputs. If passed, this takes precedence over the con defined at initialization.
        overwrite: Whether to overwrite existing tables
        lazy_execution: Whether to use lazy execution with change detection
        n_threads: Max number of jobs to run simultaneously.

    Returns:
        PhenotypeTable: The index table corresponding the cohort.
    """

    con = self._prepare_database_connector_for_execution(con)
    tables = self._prepare_tables_for_execution(con, tables)

    self.n_persons_in_source_database = (
        tables["PERSON"].distinct().count().execute()
    )

    self.build_stages(tables)

    # Apply data period filter first if specified
    if self.data_period_filter_stage:
        logger.info(f"Cohort '{self.name}': executing data period filter stage ...")
        self.data_period_filter_stage.execute(
            tables=tables,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )
        # Update tables with filtered versions (only when the node actually modified the table;
        # nodes with no relevant date columns return None and the original table is kept)
        for node in self.data_period_filter_stage.children:
            if node.table is not None:
                tables[node.domain] = node.table
        logger.info(f"Cohort '{self.name}': completed data period filter stage.")

    if self.derived_tables_stage:
        logger.info(
            f"Cohort '{self.name}': executing derived tables pre-entry stage ..."
        )
        self.derived_tables_stage.execute(
            tables=tables,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )
        logger.info(
            f"Cohort '{self.name}': completed derived tables pre-entry stage."
        )
        for node in self.derived_tables:
            tables[node.name] = PhenexTable(node.table)

    logger.info(f"Cohort '{self.name}': executing entry stage ...")

    self.entry_stage.execute(
        tables=tables,
        con=con,
        overwrite=overwrite,
        n_threads=n_threads,
        lazy_execution=lazy_execution,
    )
    self.subset_tables_entry = tables = self.get_subset_tables_entry(tables)

    logger.info(f"Cohort '{self.name}': completed entry stage.")

    if self.derived_tables_post_entry_stage:
        logger.info(
            f"Cohort '{self.name}': executing derived tables post-entry stage ..."
        )
        self.derived_tables_post_entry_stage.execute(
            tables=self.subset_tables_entry,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )
        logger.info(
            f"Cohort '{self.name}': completed derived tables post-entry stage."
        )
        entry_dates = self.entry_criterion.table.select(
            "PERSON_ID", "EVENT_DATE"
        ).rename({"INDEX_DATE": "EVENT_DATE"})
        # TODO this is a bit hacky, consider a cleaner way to handle this if we want to support post-entry derived tables in the long term i.e. a DERIVED_TABLES class that adds index table automatically if present in the source derived table.
        for node in self.derived_tables_post_entry:
            table_with_index = node.table.join(entry_dates, "PERSON_ID")
            self.subset_tables_entry[node.name] = PhenexTable(table_with_index)
        tables = self.subset_tables_entry

    logger.info(f"Cohort '{self.name}': executing index stage ...")

    self.index_stage.execute(
        tables=self.subset_tables_entry,
        con=con,
        overwrite=overwrite,
        n_threads=n_threads,
        lazy_execution=lazy_execution,
    )
    self.table = self.index_table_node.table

    logger.info(f"Cohort '{self.name}': completed index stage.")
    logger.info(f"Cohort '{self.name}': executing reporting stage ...")

    self.subset_tables_index = self.get_subset_tables_index(tables)

    # Also add derived post-entry tables to subset_tables_index, further filtered
    # to only include persons that passed all inclusion/exclusion criteria.
    if self.derived_tables_post_entry:
        index_person_ids = self.index_table_node.table.select("PERSON_ID")
        for node in self.derived_tables_post_entry:
            if node.name in self.subset_tables_entry:
                entry_tbl = self.subset_tables_entry[node.name]
                filtered_ibis = entry_tbl.table.semi_join(
                    index_person_ids, "PERSON_ID"
                )
                self.subset_tables_index[node.name] = type(entry_tbl)(filtered_ibis)

    if self.reporting_stage:
        logger.info(f"Cohort '{self.name}': executing reporting stage ...")
        self.reporting_stage.execute(
            tables=self.subset_tables_index,
            con=con,
            overwrite=overwrite,
            n_threads=n_threads,
            lazy_execution=lazy_execution,
        )

    return self.index_table

get_codelists(as_dataframe=False)

Get a dictionary of all codelists used in any phenotype in this cohort. The keys are the codelist names and the values are the codelist objects.

Source code in phenex/core/cohort.py
def get_codelists(self, as_dataframe=False):
    """
    Get a dictionary of all codelists used in any phenotype in this cohort. The keys are the codelist names and the values are the codelist objects.
    """
    top_level_nodes = (
        [self.entry_criterion]
        + self.inclusions
        + self.exclusions
        + self.characteristics
        + self.outcomes
    )
    all_nodes = top_level_nodes + sum([t.dependencies for t in top_level_nodes], [])
    codelists = {
        pt.display_name: pt.codelist
        for pt in all_nodes
        if getattr(pt, "codelist", None) is not None
    }
    if as_dataframe:
        import pandas as pd

        _dfs = []
        for name_pt, codelist in codelists.items():
            codelist_df = codelist.df
            codelist_df["phenotype"] = name_pt
            _dfs.append(codelist_df)
        codelists_df = pd.concat(_dfs, ignore_index=True)
        return codelists_df

    return codelists

get_subset_tables_entry(tables)

Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given entry_phenotype.

Source code in phenex/core/cohort.py
def get_subset_tables_entry(self, tables):
    """
    Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given entry_phenotype.
    """
    subset_tables_entry = {}
    for node in self.subset_tables_entry_nodes:
        # Skip if table is None (not found in source data)
        if node.table is None:
            continue
        if tables[node.domain] is None:
            continue
        subset_tables_entry[node.domain] = type(tables[node.domain])(node.table)
    return subset_tables_entry

get_subset_tables_index(tables)

Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given index_phenotype.

Source code in phenex/core/cohort.py
def get_subset_tables_index(self, tables):
    """
    Get the PhenexTable from the ibis Table for subsetting tables for all domains in this cohort subsetting by the given index_phenotype.
    """
    subset_tables_index = {}
    for node in self.subset_tables_index_nodes:
        # Skip if table is None (not found in source data)
        if node.table is None:
            continue
        if tables.get(node.domain) is None:
            continue
        subset_tables_index[node.domain] = type(tables[node.domain])(node.table)
    return subset_tables_index

to_dict()

Return a dictionary representation of the Node. The dictionary must contain all dependencies of the Node such that if anything in self.to_dict() changes, the Node must be recomputed.

Source code in phenex/core/cohort.py
def to_dict(self):
    """
    Return a dictionary representation of the Node. The dictionary must contain all dependencies of the Node such that if anything in self.to_dict() changes, the Node must be recomputed.
    """
    d = to_dict(self)
    # custom_reporters are runtime execution objects and cannot be meaningfully
    # serialized; drop them from the frozen cohort definition.
    d.pop("custom_reporters", None)
    return d

write_reports_to_excel(path)

Write all available reports (table1, waterfall, waterfall_detailed) to Excel files in the given directory.

Source code in phenex/core/cohort.py
def write_reports_to_excel(self, path: str):
    """Write all available reports (table1, waterfall, waterfall_detailed) to Excel files in the given directory."""
    if self.table1_node:
        self.table1_node.to_excel(os.path.join(path, "table1.xlsx"))
    if self.table1_detailed_node:
        self.table1_detailed_node.to_excel(
            os.path.join(path, "table1_detailed.xlsx")
        )
    if self.table1_outcomes_node:
        self.table1_outcomes_node.to_excel(
            os.path.join(path, "table1_outcomes.xlsx")
        )
    if self.table1_outcomes_detailed_node:
        self.table1_outcomes_detailed_node.to_excel(
            os.path.join(path, "table1_outcomes_detailed.xlsx")
        )
    if self.waterfall_node:
        self.waterfall_node.to_excel(os.path.join(path, "waterfall.xlsx"))
    if self.waterfall_detailed_node:
        self.waterfall_detailed_node.to_excel(
            os.path.join(path, "waterfall_detailed.xlsx")
        )
    for custom_reporter_node in self.custom_reporter_nodes:
        report_filename = custom_reporter_node.reporter.name
        custom_reporter_node.to_excel(os.path.join(path, report_filename + ".xlsx"))

write_reports_to_json(path)

Write all available reports as JSON files (machine-readable intermediate format).

Source code in phenex/core/cohort.py
def write_reports_to_json(self, path: str):
    """Write all available reports as JSON files (machine-readable intermediate format)."""
    if self.table1_node:
        self.table1_node.to_json(os.path.join(path, "table1.json"))
    if self.table1_detailed_node:
        self.table1_detailed_node.to_json(
            os.path.join(path, "table1_detailed.json")
        )
    if self.table1_outcomes_node:
        self.table1_outcomes_node.to_json(
            os.path.join(path, "table1_outcomes.json")
        )
    if self.table1_outcomes_detailed_node:
        self.table1_outcomes_detailed_node.to_json(
            os.path.join(path, "table1_outcomes_detailed.json")
        )
    if self.waterfall_node:
        self.waterfall_node.to_json(os.path.join(path, "waterfall.json"))
    if self.waterfall_detailed_node:
        self.waterfall_detailed_node.to_json(
            os.path.join(path, "waterfall_detailed.json")
        )
    for custom_reporter_node in self.custom_reporter_nodes:
        report_filename = custom_reporter_node.reporter.name
        custom_reporter_node.to_json(os.path.join(path, report_filename + ".json"))