TimeToEvent
Bases: Reporter
Perform a time to event analysis using Kaplan-Meier estimation.
This reporter generates: 1. A private patient-level time-to-event table (_tte_table) for intermediate processing 2. Aggregated survival/risk data in self.df combining results from all outcomes 3. Kaplan-Meier survival curves
The patient-level table (_tte_table) contains one row per patient with: - Index date for each patient - Event dates for all outcomes (NULL if did not occur) - Event dates for all right censoring events (NULL if did not occur) - End of study period date (if provided) - Days from index to each event - Indicator variables for whether the first event was the outcome of interest
The aggregated output (self.df) contains survival function estimates and event counts for each outcome, suitable for reporting and visualization.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
right_censor_phenotypes
|
Optional[List[Phenotype]]
|
A list of phenotypes that should be used as right censoring events. Suggested are death and end of followup. |
None
|
end_of_study_period
|
Optional[datetime]
|
A datetime defining the end of study period. |
None
|
decimal_places
|
int
|
Number of decimal places for rounding survival probabilities. Default: 4 |
4
|
pretty_display
|
bool
|
If True, format output for display. Default: True |
True
|
Source code in phenex/reporting/time_to_event.py
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execute(cohort)
Execute the time to event analysis for a provided cohort.
This generates: 1. Patient-level time-to-event table (stored in self._tte_table) 2. Aggregated survival/risk data from Kaplan-Meier fits (stored in self.df) 3. Kaplan-Meier plots
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
cohort
|
Cohort
|
The cohort for which the time to event analysis should be performed. |
required |
Returns:
| Name | Type | Description |
|---|---|---|
DataFrame
|
DataFrame with aggregated survival function estimates and event counts for all outcomes. |
|
Schema |
DataFrame
|
|
Source code in phenex/reporting/time_to_event.py
fit_kaplan_meier_for_phenotype(phenotype)
Fit a Kaplan-Meier model for a specific phenotype outcome.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
phenotype
|
The outcome phenotype to analyze |
required |
Returns:
| Name | Type | Description |
|---|---|---|
KaplanMeierFitter |
Fitted KM model |
Source code in phenex/reporting/time_to_event.py
get_pretty_display()
Return a formatted version of the reporter's results for display.
Default implementation returns a copy of self.df with: - Numeric values rounded to decimal_places - NaN values replaced with empty strings for cleaner display
Subclasses can override this method for custom formatting (e.g., phenotype display names).
Returns:
| Type | Description |
|---|---|
DataFrame
|
pd.DataFrame: Formatted copy of the results |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined |
Source code in phenex/reporting/reporter.py
plot_multiple_kaplan_meier(xlim=None, ylim=None, n_cols=3, outcome_indices=None, path_dir=None)
For each outcome, plot a kaplan meier curve.
Source code in phenex/reporting/time_to_event.py
plot_single_kaplan_meier(outcome_index=0, xlim=None, ylim=None, path_dir=None)
For each outcome, plot a kaplan meier curve.
Source code in phenex/reporting/time_to_event.py
to_csv(filename)
Export reporter results to CSV format.
Default implementation exports self.df if it exists. Subclasses can override for custom behavior. If pretty_display=True, formats the DataFrame before export.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
filename
|
str
|
Path to the output file (relative or absolute, with or without .csv extension) |
required |
Returns:
| Name | Type | Description |
|---|---|---|
str |
str
|
Full path to the created file |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined (call execute() first) |
Source code in phenex/reporting/reporter.py
to_excel(filename)
Export reporter results to Excel format.
Default implementation exports self.df if it exists. Subclasses can override for custom behavior. If pretty_display=True, formats the DataFrame before export using get_pretty_display().
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
filename
|
str
|
Path to the output file (relative or absolute, with or without .xlsx extension) |
required |
Returns:
| Name | Type | Description |
|---|---|---|
str |
str
|
Full path to the created file |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined (call execute() first) |
ImportError
|
If openpyxl is not installed |
Source code in phenex/reporting/reporter.py
to_html(filename)
Export reporter results to HTML format.
Default implementation exports self.df if it exists. Subclasses can override for custom behavior. If pretty_display=True, formats the DataFrame before export.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
filename
|
str
|
Path to the output file (relative or absolute, with or without .html extension) |
required |
Returns:
| Name | Type | Description |
|---|---|---|
str |
str
|
Full path to the created file |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined (call execute() first) |
Source code in phenex/reporting/reporter.py
to_markdown(filename)
Export reporter results to Markdown format.
Default implementation exports self.df if it exists. Subclasses can override for custom behavior. If pretty_display=True, formats the DataFrame before export.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
filename
|
str
|
Path to the output file (relative or absolute, with or without .md extension) |
required |
Returns:
| Name | Type | Description |
|---|---|---|
str |
str
|
Full path to the created file |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined (call execute() first) |
ImportError
|
If tabulate is not installed (required for df.to_markdown()) |
Source code in phenex/reporting/reporter.py
to_word(filename)
Export reporter results to Microsoft Word format.
Default implementation exports self.df as a simple table if it exists. Subclasses can override for custom formatting (headers, styling, etc). If pretty_display=True, formats the DataFrame before export using get_pretty_display().
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
filename
|
str
|
Path to the output file (relative or absolute, with or without .docx extension) |
required |
Returns:
| Name | Type | Description |
|---|---|---|
str |
str
|
Full path to the created file |
Raises:
| Type | Description |
|---|---|
AttributeError
|
If self.df is not defined (call execute() first) |
ImportError
|
If python-docx is not installed |